The charity is appealing for knitters to help offer comfort, warmth and security to animals, as the cost-of-living crisis leaves many families struggling to care for their pets.
Blankets will be distributed through the RSPCA's Pet Food Bank Partnership as part of its Big Give Back to Animals appeal.
Alison Fletcher, the RSPCA's national lead for pet food banks, said: "Every pet deserves warmth, comfort and care, especially during winter."
The charity hopes the initiative will raise awareness of the role animals play in our lives and help prevent welfare issues.
"Sadly, we've seen reports of neglect and abandonment surge this year, indicating that many pet owners are struggling," Miss Fletcher said.
